Adenovirus (HAdV) Infection Tests and Treatment
Human adenovirus (HAdV) belongs to the genus Mammalian
adenovirus. It is an unencapsulated double-stranded DNA virus. It can be
divided into 7 subgenera A-G. At least 90 genotypes have been found. The
tissues of the virus have different tropism, which causes different diseases of
tissues and organs. Among them, the adenoviruses related to respiratory
diseases are mainly B, C and E subgenus adenoviruses. Etiological monitoring
data show that subgenus B HAdV-7 and HAdV-3 are the major adenovirus types that
cause respiratory infectious diseases in China. HAdV-1 and HAdV-2 in group C
are also not uncommon, especially in southern China.
HAdV-55 is gradually becoming widespread in China.
Adenovirus is a common pathogen that can cause infection and disease in humans, and most cases have mild symptoms
Because different adenoviruses have different tropism in
human tissues, adenovirus infection can cause a variety of clinical
manifestations and diseases, including respiratory diseases (such as common
cold, bronchitis, pneumonia, etc.), and digestive diseases (such as diarrhea,
gastroenteritis, etc.), Ocular conjunctivitis, cystitis and neurological
diseases. Individual cases can appear severe and critical, and even die. In
particular, patients with weak immune systems or chronic respiratory diseases,
heart diseases, etc. are at higher risk of causing serious diseases after
infection with adenovirus.
Which people are susceptible to adenovirus?
People of all ages can be infected with adenovirus. Patients
with weak immune system or chronic respiratory disease, heart disease and other
infections have a higher risk of causing serious diseases.
How is human adenovirus transmitted?
1. Droplet spread
Adenovirus is the main mode of transmission of respiratory
infections, such as patients coughing or sneezing;
2. Contact spread
If your hands touch the adenovirus-contaminated objects or
surfaces, touch your mouth, nose, or eyes without washing your hands.
3. Gastrointestinal infections
Can be transmitted through the feces of infected individuals, such
as during diaper changes.
How to prevent human adenovirus infection?
There are currently no adenovirus vaccines available for the
general population, and vaccines against HAdV-4 and HAdV-7 are only used in the
US military.
The main measures to prevent adenovirus infection include
washing hands frequently, avoiding touching the eyes, nose and mouth with
unclean hands, and avoiding close contact with patients.
What if I get sick?
If infected with adenovirus, those with mild symptoms try to
stay at home in isolation, reduce going out and avoid going to public places.
- Cover your nose and mouth when coughing or sneezing.
- Avoid sharing cups and cutlery with others.
- Avoid close contact with others.
How to treat human adenovirus infection?
At present, there are no specific antiviral treatment drugs
for adenoviral infections in China. Most people with adenovirus infection do
not have severe symptoms and can take general treatment measures to relieve the
symptoms. Severe cases require hospitalization, mainly symptomatic and
supportive care.
Adenovirus infection
Adenovirus is an unencapsulated particle with a diameter of
70 to 90 nm. It consists of 252 shell particles arranged in a corpus planer.
The capsid is a linear double-stranded DNA molecule.
The adenovirus is divided
into two genera and has about 100 serotypes. Generally cause respiratory
discomfort, have carcinogenic ability for rodents, or can transform rodent
cells cultured in vitro.
What I must see when going to the hospital for Adeno virus infection?
What department to link: Department of Respiratory Medicine,
Department of Infectious Diseases
Which symptoms: fever, cough, sore throat,
runny nose, hematuria, diarrhea, abdominal pain, corneal and conjunctival
dryness, frequent urination with urgency and pain, dysuria and urinary
retention, infectious rhinitis, pharyngitis, glossitis, gingivitis
Examinations required: blood routine, direct smear, virus
isolation, serology
Caused by disease: bronchitis
Treatment method: drug treatment
Medical Tips
Commonly Used Drugs:
Interferon
Whether infection:
Yes
Prevalence: 2.3% of
the population
Treatment period: 14
days
What Diet should be avoided under Adeno virus infection?
- Should eat heat-clearing and detoxifying foods
- Should eat foods to enhance human immunity
- Should eat dietary fiber foods.
Etiology / Symptoms / Examination Identification / Complications / Preventive Treatment / Diet
How does an adenovirus infection cause it?
Adenoviruses were found to have 6 subtypes (A to F) and 47
different serotypes (typed by neutralization test). About 20 subtypes are known
to infect humans.
The virus is an icosahedral capsid with a diameter of 70-80
nm, and the core contains double-stranded DNA. Unstable to heat and acids.
Because it does not contain lipids, it has strong resistance to lipid
solubilizers such as bile salts, so it can survive in the intestine.
What are the symptoms of an adenovirus infection?
1. The rapid diagnosis method uses a polyvalent adenovirus
fluorescent immune serum to stain exfoliated cell smears taken from the
pharynx. Bright fluorescence in the nucleus of exfoliated cells can be seen
under a fluorescence microscope, indicating that the virus is positive.
2.
Virus isolation: Passaged monolayer human epithelial cells were inoculated with
pharyngeal secretions, sputum, conjunctival scrape and fresh urine of different
clinical types.
What are the test items for adenovirus infection?
The total number of white blood cells is normal or slightly
reduced, and the lymphocytes are relatively increased. In patients with
pneumonia, X-ray chest radiographs have a sheet infiltration on one or both
sides, and there may be a small amount of pleural effusion.
1. Isolation and
culture: Specimens should be collected from the infected site as soon as
possible. Collect the throat, eye secretions, feces and urine of patients,
treat with antibiotics overnight, centrifuge the supernatant to inoculate
sensitive cells.
Causes Symptoms
Examination Complications Prevention Treatment What to eat
What causes human adenovirus infection?
Clinical manifestations of adenovirus:
1. Onset latency period is 3 to 8 days.
Generally, fever is rapid, and high fever above 39 ° C usually occurs from the
1st to 2nd days, and it is mostly stagnation or irregular high fever from the
3rd to 4th days.
2. The highest body temperature of more than 3/5
cases exceeds 40 ° C. 2. Most children with respiratory symptoms have symptoms
since onset.
Q: What about adenovirus infection?
"Hello, it can
cause infections in humans, apes, horses, pigs, sheep, dogs, etc. Experiments
have found that they can cause carcinogenesis in animals.
They have not been shown to cause human tumors, but can cause
a variety of infectious diseases in humans. Acid is unstable. Because it does
not contain lipids, it has strong resistance to lipid solubilizers such as bile
salts. "
What is going on with adenovirus infection?
Adenovirus is a very common virus in the respiratory tract.
Infection can be prevalent throughout the year and is found in all organs of
the human body. Upper respiratory tract infections are more common in common
colds, pharyngitis and tonsillitis. Lower respiratory tract infections are
found in bronchitis and pneumonia. Gain lasting immunity.
Related disease symptoms: Frequent urination, sore throat,
urgency, lung snoring
Tags: What is adenovirus infection? What
are the clinical manifestations of adenovirus infection? What are the symptoms
of adenovirus infection? What are the clinical symptoms of adenovirus
infection? What are the causes and pathogenesis of adenovirus infection? Which
tests should be done for adenovirus infection? What diseases are adenovirus
infections easy to confuse? What diseases can adenovirus infection be
complicated by?
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