What are Adenovirus (HAdV) Tests Treatment?


Adenovirus (HAdV) Infection Tests and Treatment

Human adenovirus (HAdV) belongs to the genus Mammalian adenovirus. It is an unencapsulated double-stranded DNA virus. It can be divided into 7 subgenera A-G. At least 90 genotypes have been found. The tissues of the virus have different tropism, which causes different diseases of tissues and organs. Among them, the adenoviruses related to respiratory diseases are mainly B, C and E subgenus adenoviruses. Etiological monitoring data show that subgenus B HAdV-7 and HAdV-3 are the major adenovirus types that cause respiratory infectious diseases in China. HAdV-1 and HAdV-2 in group C are also not uncommon, especially in southern China.
HAdV-55 is gradually becoming widespread in China.

Adenovirus is a common pathogen that can cause infection and disease in humans, and most cases have mild symptoms

Because different adenoviruses have different tropism in human tissues, adenovirus infection can cause a variety of clinical manifestations and diseases, including respiratory diseases (such as common cold, bronchitis, pneumonia, etc.), and digestive diseases (such as diarrhea, gastroenteritis, etc.), Ocular conjunctivitis, cystitis and neurological diseases. Individual cases can appear severe and critical, and even die. In particular, patients with weak immune systems or chronic respiratory diseases, heart diseases, etc. are at higher risk of causing serious diseases after infection with adenovirus.

Which people are susceptible to adenovirus?

People of all ages can be infected with adenovirus. Patients with weak immune system or chronic respiratory disease, heart disease and other infections have a higher risk of causing serious diseases.

How is human adenovirus transmitted?

   1.    Droplet spread

Adenovirus is the main mode of transmission of respiratory infections, such as patients coughing or sneezing;

   2.    Contact spread

If your hands touch the adenovirus-contaminated objects or surfaces, touch your mouth, nose, or eyes without washing your hands.

   3.    Gastrointestinal infections

     Can be transmitted through the feces of infected individuals, such as during diaper changes.

How to prevent human adenovirus infection?

There are currently no adenovirus vaccines available for the general population, and vaccines against HAdV-4 and HAdV-7 are only used in the US military.

The main measures to prevent adenovirus infection include washing hands frequently, avoiding touching the eyes, nose and mouth with unclean hands, and avoiding close contact with patients.

What if I get sick?

If infected with adenovirus, those with mild symptoms try to stay at home in isolation, reduce going out and avoid going to public places.

  • Cover your nose and mouth when coughing or sneezing.
  • Avoid sharing cups and cutlery with others.
  • Avoid close contact with others.

How to treat human adenovirus infection?

At present, there are no specific antiviral treatment drugs for adenoviral infections in China. Most people with adenovirus infection do not have severe symptoms and can take general treatment measures to relieve the symptoms. Severe cases require hospitalization, mainly symptomatic and supportive care.

Adenovirus infection

Adenovirus is an unencapsulated particle with a diameter of 70 to 90 nm. It consists of 252 shell particles arranged in a corpus planer. The capsid is a linear double-stranded DNA molecule.
The adenovirus is divided into two genera and has about 100 serotypes. Generally cause respiratory discomfort, have carcinogenic ability for rodents, or can transform rodent cells cultured in vitro.

What I must see when going to the hospital for Adeno virus infection?

What department to link: Department of Respiratory Medicine, Department of Infectious Diseases
 Which symptoms: fever, cough, sore throat, runny nose, hematuria, diarrhea, abdominal pain, corneal and conjunctival dryness, frequent urination with urgency and pain, dysuria and urinary retention, infectious rhinitis, pharyngitis, glossitis, gingivitis
Examinations required: blood routine, direct smear, virus isolation, serology
Caused by disease: bronchitis
Treatment method: drug treatment

Medical Tips

 Commonly Used Drugs: Interferon
  Whether infection: Yes
  Prevalence: 2.3% of the population
  Treatment period: 14 days

What Diet should be avoided under Adeno virus infection?

  •  Should eat heat-clearing and detoxifying foods
  •  Should eat foods to enhance human immunity
  •  Should eat dietary fiber foods.

Etiology / Symptoms / Examination Identification / Complications / Preventive Treatment / Diet

How does an adenovirus infection cause it?

Adenoviruses were found to have 6 subtypes (A to F) and 47 different serotypes (typed by neutralization test). About 20 subtypes are known to infect humans.

The virus is an icosahedral capsid with a diameter of 70-80 nm, and the core contains double-stranded DNA. Unstable to heat and acids.

Because it does not contain lipids, it has strong resistance to lipid solubilizers such as bile salts, so it can survive in the intestine.
Adeno virus HAdV Tests and Treatment

What are the symptoms of an adenovirus infection?

1. The rapid diagnosis method uses a polyvalent adenovirus fluorescent immune serum to stain exfoliated cell smears taken from the pharynx. Bright fluorescence in the nucleus of exfoliated cells can be seen under a fluorescence microscope, indicating that the virus is positive.

2. Virus isolation: Passaged monolayer human epithelial cells were inoculated with pharyngeal secretions, sputum, conjunctival scrape and fresh urine of different clinical types.

What are the test items for adenovirus infection?

The total number of white blood cells is normal or slightly reduced, and the lymphocytes are relatively increased. In patients with pneumonia, X-ray chest radiographs have a sheet infiltration on one or both sides, and there may be a small amount of pleural effusion.
1. Isolation and culture: Specimens should be collected from the infected site as soon as possible. Collect the throat, eye secretions, feces and urine of patients, treat with antibiotics overnight, centrifuge the supernatant to inoculate sensitive cells.

Causes Symptoms Examination Complications Prevention Treatment What to eat

What causes human adenovirus infection?

Clinical manifestations of adenovirus:
1.    Onset latency period is 3 to 8 days. Generally, fever is rapid, and high fever above 39 ° C usually occurs from the 1st to 2nd days, and it is mostly stagnation or irregular high fever from the 3rd to 4th days.
2.     The highest body temperature of more than 3/5 cases exceeds 40 ° C. 2. Most children with respiratory symptoms have symptoms since onset.

    Q: What about adenovirus infection?

    "Hello, it can cause infections in humans, apes, horses, pigs, sheep, dogs, etc. Experiments have found that they can cause carcinogenesis in animals.
They have not been shown to cause human tumors, but can cause a variety of infectious diseases in humans. Acid is unstable. Because it does not contain lipids, it has strong resistance to lipid solubilizers such as bile salts. "

What is going on with adenovirus infection?

Adenovirus is a very common virus in the respiratory tract. Infection can be prevalent throughout the year and is found in all organs of the human body. Upper respiratory tract infections are more common in common colds, pharyngitis and tonsillitis. Lower respiratory tract infections are found in bronchitis and pneumonia. Gain lasting immunity.
Related disease symptoms: Frequent urination, sore throat, urgency, lung snoring

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